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Antigenic Specificity | ACOT8 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total ACOT8 protein. Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH. May mediate Nef-induced down-regulation of CD4. Major thioesterase in peroxisomes. Competes with BAAT (Bile acid CoA: amino acid N-acyltransferase) for bile acid-CoA substrate (such as chenodeoxycholoyl-CoA). Shows a preference for medium-length fatty acyl-CoAs By similarity. May be involved in the metabolic regulation of peroxisome proliferation.Watanabe H., Biochem. Biophys. Res. Commun. 238:234-239(1997).Liu L.X., J. Biol. Chem. 272:13779-13785(1 |
Immunogen | Immunogen Type: Peptide Immunogen Description: Synthesized peptide derived from internal of human ACOT8. |
Other Names | [ACTE-III; ACTEIII; acyl-CoA thioesterase 8; acyl-coenzyme A thioesterase 8; choloyl-coenzyme A thioesterase] |
Gene, Accession # | [ACOT8], Gene ID: 10005, NCBI: NP_005460.2, UniProt: O14734 |
Catalog # | MBS9402185 |
Price | $200, $255 |
Order / More Info | ACOT8 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |