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Antigenic Specificity | HIP2 (Center), 109-139 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse (predicted reactivity: bovine) |
Isotype | n/a |
Format | purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 2 |
Applications | ELISA (EIA), Immunohistochemistry (IHC), Western Blot (WB), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This HIP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 109-139 amino acids from the Central region of human HIP2. HIP2 belongs to the ubiquitin-conjugating enzyme family. It binds selectively to a large region at the N terminus of huntingtin. This interaction is not influenced by the length of the huntingtin polyglutamine tract. This protein has been implicated in the degradation of huntingtin and suppression of apoptosis. |
Immunogen | n/a |
Other Names | [Ubiquitin-conjugating enzyme E2 K; Huntingtin-interacting protein 2; HIP-2; Ubiquitin carrier protein; Ubiquitin-conjugating enzyme E2-25 kDa; Ubiquitin-conjugating enzyme E2(25K); Ubiquitin-conjugating enzyme E2-25K; Ubiquitin-protein ligase; UBE2K; HIP2; LIG] |
Gene, Accession # | [UBE2K], Gene ID: 3093, NCBI: NP_001104582.1, UniProt: P61086 |
Catalog # | MBS9213324 |
Price | $165, $370 |
Order / More Info | HIP2 (Center), 109-139 Antibody from MYBIOSOURCE INC. |
Product Specific References | Furukawa, Y., et al., Electrophoresis 21(2):338-346 (2000). Kikuchi, J., et al., Arterioscler. Thromb. Vasc. Biol. 20(1):128-134 (2000). Petersen, A., et al., Exp. Neurol. 157(1):1-18 (1999). Kalchman, M.A., et al., J. Biol. Chem. 271(32):19385-19394 (1996). |