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Antigenic Specificity | PDCD4 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mg |
Concentration | 1 mg/mL |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | PDCD4 Antibody: Apoptosis, also known as programmed cell death, plays major roles in development and normal tissue turnover in addition to tumor formation. During this process, the expression patterns of numerous genes are radically altered. One such gene is the programmed cell death protein 4 (PDCD4), whose expression was found to be upregulated in all cell lines following the onset of apoptosis. PDCD4 encodes a tumor suppressor protein whose expression is lost in carcinomas of breast, colon, lung and prostate. It can bind to and inhibit the helicase activity of the eukaryotic translation initiation factor 4A and inhibit the transactivation and transformation mediated by the transcription factor AP-1. The kinase Akt regulates PDCD4 by phos |
Immunogen | Immunogen: PDCD4 antibody was raised against a 19 amino acid synthetic peptide from near the carboxy terminus of human PDCD4. Buffer: PDCD4 Antibody is supplied in PBS containing 0.02% sodium azide. |
Other Names | [PDCD4; H731; H731; Programmed cell death protein 4; Neoplastic transformation inhibitor protein; programmed cell death 4 (neoplastic transformation inhibitor)], [PDCD4; PDCD4; H731; H731] |
Gene, Accession # | [PDCD4], Gene ID: 27250, NCBI: NP_663314, UniProt: Q53EL6 |
Catalog # | MBS151051 |
Price | $375 |
Order / More Info | PDCD4 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |