CCM2 Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-CCM2 antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | CCM2 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | antigen affinity purified |
| Size | 0.1 mL |
| Concentration | 0.8mg/ml |
| Applications | Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | The antibody detects endogenous levels of total CCM2 protein. This gene encodes a scaffold protein that functions in the stress-activated p38 Mitogen-activated protein kinase (MAPK) signaling cascade. The protein interacts with SMAD specific E3 ubiquitin protein ligase 1 (also known as SMURF1) via a phosphotyrosine binding domain to promote RhoA degradation. The protein is required for normal cytoskeletal structure, cell-cell interactions, and lumen formation in endothelial cells. Mutations in this gene result in cerebral cavernous malformations. Multiple transcript variants encoding different isoforms have been found for this gene. |
| Immunogen | Immunogen: Synthetic protein corresponding to residues near the C terminal of human CCM2 Immunogen Type: Peptide |
| Other Names | [OSM; C7orf22; PP10187] |
| Gene, Accession # | [CCM2], Gene ID: 83605, NCBI: BC004903, UniProt: Q9BSQ5 |
| Catalog # | MBS9429571 |
| Price | $255 |
| Order / More Info | CCM2 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
Profile of MYBIOSOURCE INC.
Return to Antibodies