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Antigenic Specificity | Plakophilin-1 (PKP1) |
Clone | [10B2] |
Host Species | Mouse |
Reactive Species | human, mouse. |
Isotype | IgG1 |
Format | unconjugated |
Size | 0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml) |
Concentration | n/a |
Applications | Flow Cytometry (FC/FACS), Immunofluorescence (IF), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Recognizes a protein of 75kDa, identified as Plakophilin-1. Its epitope maps between aa 1-27 human Plakophilin-1. Plakophilins 1, 2, 3 and 4 (PKP1-4) influence development and participate in linking cadherins to cytoskeletal intermediate filaments. Plakophilins 1-4 contain arm-repeat (armadillo) domains and localize to nuclei and cell desmosomes (cell-cell junctions found in suprabasal layers of stratifying epithelia that undergo mechanical stress). Plakophilin 2 is important for desmosome assembly and is an essential morphogenic factor and architectural component of the heart. |
Immunogen | Immunogen: N-terminus of human Plakophilin-1 protein Cellular Localization: Cell Surface and nuclear |
Other Names | [B6P; Band 6 protein; PKP1; Plakophilin-1 (ectodermal dysplasia/skin fragility syndrome)] |
Gene, Accession # | [PKP1], Gene ID: 5317, NCBI: NP_000290.2, UniProt: Q13835 |
Catalog # | MBS4380158 |
Price | $190, $340, $340 |
Order / More Info | Plakophilin-1 (PKP1) Antibody from MYBIOSOURCE INC. |
Product Specific References | Hadiji-Abbes, N. et al. 2014. Negative control glucose dependent mediated by the PreS2 region on the translation efficiency of the reporter Sh-bleomycin gene in Saccharomyces cerevisiae. FEMS Yeast Res. 14: 357-63. |