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Antigenic Specificity | IGF2BP1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | RNA-binding factor that recruits target transcripts to cytoplasmic protein-RNA complexes (mRNPs). This transcript 'caging' into mRNPs allows mRNA transport and transient storage. It also modulates the rate and location at which target transcripts encounter the translational apparatus and shields them from endonuclease attacks or microRNA-mediated degradation. Plays a direct role in the transport and translation of transcripts required for axonal regeneration in adult sensory neurons. Regulates localized beta-actin/ACTB mRNA translation, a crucial process for cell polarity, cell migration and neurite outgrowth. Co-transcriptionally associates with the ACTB mRNA in the nucleus. This binding involves a conserved 54-nucleotide element in the AC |
Immunogen | Immunogen: A synthetic peptide corresponding to a sequence within amino acids 500 to the C-terminus of human IGF2BP1 (NP 006537.3). |
Other Names | [IMP1; ZBP1; CRDBP; IMP-1; CRD-BP; VICKZ1] |
Gene, Accession # | [IGF2BP1], Gene ID: 10642, NCBI: Q9NZI8.2, UniProt: Q9NZI8 |
Catalog # | MBS8544421 |
Price | $280 |
Order / More Info | IGF2BP1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |