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Antigenic Specificity | Vimentin (Mesenchymal Cell Marker) |
Clone | [VM452] |
Host Species | Mouse |
Reactive Species | human, cow, dog, cat, porcine, goat, chickendoes not react with mouse or rat. |
Isotype | IgG1, kappa |
Format | CF488 conjugate |
Size | 0.5 mL |
Concentration | n/a |
Applications | Flow Cytometry (FC/FACS), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This MAb reacts with a 58kDa protein identified as vimentin. It shows no cross-reaction with other closely related intermediate filament proteins (IFP's) such as desmin, keratin, neurofilament, and glial fibrillary acid protein.Anti-vimentin alone is of limited value as a diagnostic tool; however, when used in panels with other antibodies, it is useful for the sub-classification of a given tumor. Expression of vimentin, when used in conjunction with anti-keratin, is helpful when distinguishing melanomas from undifferentiated carcinomas and large cell lymphomas. All melanomas and Schwannomas react strongly with anti-vimentin. It labels a variety of mesenchymal cells, including melanocytes, lymphocytes, endothelial cells, and fibroblasts. Non |
Immunogen | Immunogen: Recombinant human vimentin protein |
Other Names | [VIM] |
Gene, Accession # | [VIM], Gene ID: 7431, NCBI: NP_003371.2, UniProt: P08670 |
Catalog # | MBS4381335 |
Price | $340 |
Order / More Info | Vimentin (Mesenchymal Cell Marker) Antibody from MYBIOSOURCE INC. |
Product Specific References | Osborn M et. al. European Journal of Cell Biology. 1984; 34:137-143 |