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Antigenic Specificity | CREB (Ab-129/133) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total CREB protein. Phosphorylation-dependent transcription factor that stimulates transcription upon binding to the DNA cAMP response element (CRE), a sequence present in many viral and cellular promoters. Transcription activation is enhanced by the TORC coactivators which act independently of Ser-133 phosphorylation. Involved in different cellular processes including the synchronization of circadian rhythmicity and the differentiation of adipose cells.Xing J, et al. (1998) Mol Cell Biol 18(4): 1946-55.Tan Y, et al.(1996) EMBO J; 15(17): 4629-42.Hao, M. et al. (1996) J. Biol. Chem. 271, 29380-29385.Mayo LD, et al. (2001) Biol Chem; 276(27): 25184-9.Lu, H. et al. (1997) Mol. Cell. Biol. 17, 5923-59 |
Immunogen | Immunogen Type: Peptide Immunogen Description: Synthesized non-phosphopeptide derived from human CREB around the phosphorylation site of serine 129 or serine 133(S-R-R-P-S). |
Other Names | [cAMP responsive element binding protein 1; cAMP-response element binding protein; CREB-1; CREB1] |
Gene, Accession # | [CREB], Gene ID: 1385, NCBI: NP_004370.1, UniProt: P16220 |
Catalog # | MBS9411911 |
Price | $200, $255 |
Order / More Info | CREB (Ab-129/133) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |