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Antigenic Specificity | HSPB8 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.05 mL, 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The protein encoded by this gene belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule. The expression of this gene in induced by estrogen in estrogen receptor-positive breast cancer cells, and this protein also functions as a chaperone in association with Bag3, a stimulator of macroautophagy. Thus, this gene appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in this gene have been associated with different neuromuscular diseases, including Charcot-Marie-Tooth disease. |
Immunogen | Immunogen: Recombinant Protein |
Other Names | [H11; HMN2; CMT2L; DHMN2; E2IG1; HMN2A; HSP22], [HSPB8; HSPB8; H11; HMN2; CMT2L; DHMN2; E2IG1; HMN2A; HSP22; CRYAC; E2IG1; HSP22; HspB8] |
Gene, Accession # | [HSPB8], Gene ID: 26353, NCBI: Q9UJY1.1, UniProt: Q9UJY1 |
Catalog # | MBS129059 |
Price | $200, $275, $430 |
Order / More Info | HSPB8 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |