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Antigenic Specificity | SET7 (C-term), 289-317 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 2 |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This SET7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 289-317 amino acids from the C-terminal region of human SET7. Histone methyltransferases (HMTases) selectively methylate evolutionarily conserved arginine or lysine residues, primarily in the N-terminal tails of histones H3 and H4. Signal transduction pathways affecting the N-terminal tails of histones lead to a number of post-translational modifications including acetylation, phosphorylation, poly(ADP-ribosylation), ubiquitination and methylation. These modifications play critical roles in regulating chromatin structure and gene expression. Set7/9 is a histone specific HMTase that methylates histone H3 lysine 4. Set7/9 transfers methyl gr |
Immunogen | n/a |
Other Names | [Histone-lysine N-methyltransferase SETD7; Histone H3-K4 methyltransferase SETD7; H3-K4-HMTase SETD7; Lysine N-methyltransferase 7; SET domain-containing protein 7; SET7/9; SETD7; KIAA1717; KMT7; SET7; SET9] |
Gene, Accession # | [SETD7], Gene ID: 80854, NCBI: NP_085151.1, UniProt: Q8WTS6 |
Catalog # | MBS9202229 |
Price | $165, $370 |
Order / More Info | SET7 (C-term), 289-317 Antibody from MYBIOSOURCE INC. |
Product Specific References | Chuikov, S., et al., Nature 432(7015):353-360 (2004). Wysocka, J., et al., Genes Dev. 17(7):896-911 (2003). Xiao, B., et al., Nature 421(6923):652-656 (2003). Kwon, T., et al., EMBO J. 22(2):292-303 (2003). Nishioka, K., et al., Genes Dev. 16(4):479-489 (2002). |