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Antigenic Specificity | Aldh5A1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Aldh5A1 is a member of the aldehyde dehydrogenase superfamily, a group of NAD(P)(+)-dependent enzymes that catalyze the oxidation of a wide spectrum of aliphatic and aromatic aldehydes. Aldehyde dehydrogenase enzymes are thought to play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. Aldh5A1 is a mitochondrial NAD(+)-dependent succinic semialdehyde dehydrogenase. A deficiency of this enzyme, known as 4-hydroxybutyricaciduria, results in a disorder of the neurotransmitter 4-aminobutyric acid (GABA). Symptoms usually include static encephalopathy, associated with developmental delays, hypotonia, ataxia, speech defects, and seizures. At least two isoforms of Aldh5A1 are known to exist. |
Immunogen | Immunogen Type: Peptide Immunogen Description: Raised against a 22 amino acid peptide near the carboxy terminus of the human Aldh5A1. |
Other Names | [Aldh5A1, Aldehyde dehydrogenase family5 member A1, succinate-semialdehyde dehydrogenase, SSDH, SSADH] |
Gene, Accession # | [Aldh5A1], Gene ID: 7915, NCBI: NP_733936 |
Catalog # | MBS9412954 |
Price | $320 |
Order / More Info | Aldh5A1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |