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Antigenic Specificity | Carcinoembryonic antigen, CEA |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), Immunocytochemistry (ICC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Carcinoembryonic antigen (CEA) is a glycoprotein involved in cell adhesion. It is normally produced during fetal development, but the production of CEA stops before birth. Therefore, it is not usually present in the blood of healthy adults, although levels are raised in heavy smokers. CEA expression is used clinically to monitor patients with colorectal and other cancers and that a subset of these patients have extraordinarily high CEA levels that cannot be attributed solely to tumor load. In addition, elevated levels of serum CEA are found in patients with benign liver disease including cirrhosis, biliary obstruction, and hepatitis. CEA may have a role as a facilitator of hepatic metastasis.1 |
Immunogen | Immunogen: A synthetic peptide (conjugated with KLH) corresponding to the region of human CEA. |
Other Names | n/a |
Gene, Accession # | [CEA], NCBI: AAA51963.1 |
Catalog # | MBS355125 |
Price | $275 |
Order / More Info | Carcinoembryonic antigen, CEA Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Zimmer, R., Thomas, P. Mutations in the carcinoembryonic antigen gene in colorectal cancer patients: implications on liver metastasis. Cancer Res. 61: 2822-2826, 2001. |