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Antigenic Specificity | ZBTB16 |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | affinity purified |
Size | 0.05 mL, 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: ZBTB16 antibody detects endogenous levels of total ZBTB16. Description: This gene is a member of the Krueppel C2H2-type zinc-finger protein family and encodes a zinc finger transcription factor that contains nine Kruppel-type zinc finger domains at the carboxyl terminus. This protein is located in the nucleus, is involved in cell cycle progression, and interacts with a histone deacetylase. Specific instances of aberrant gene rearrangement at this locus have been associated with acute promyelocytic leukemia (APL). Alternate transcriptional splice variants have been characterized.Function: Acts as a transcriptional repressor (PubMed:24359566). May play a role in myeloid maturation and in the development and/or maintenance of |
Immunogen | Immunogen: Purified recombinant fragment of human ZBTB16 expressed in E. Coli Subcellular Location: Nucleus. Tissue Specificity: Within the hematopoietic system, PLZF is expressed in bone marrow, early myeloid cell lines and peripheral blood mononuclear cells. Also expressed in the ovary, and at lower levels, in the kidney and lung. |
Other Names | [AI467657; lu; PLZF; Promyelocytic leukemia zinc finger protein; ZBT16_HUMAN; ZBTB16; Zfp145; Zinc finger and BTB domain containing 16; zinc finger and BTB domain containing protein 16; Zinc finger and BTB domain-containing protein 16; Zinc finger protein 145 (Kruppel like expressed in promyelocytic leukemia); Zinc finger protein 145; Zinc finger protein PLZF; Znf145] |
Gene, Accession # | [ZBTB16], Gene ID: 7704, NCBI: NP_001018011.1, UniProt: Q05516 |
Catalog # | MBS9602475 |
Price | $235, $295, $370 |
Order / More Info | ZBTB16 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |