PIWIL2 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPIWIL2
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatpeptide affinity purified
Size0.1 mL, 0.2 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC), ELISA (EIA)
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DescriptionSpecificity: PIWIL2 antibody detects endogenous levels of total PIWIL2. Description: PIWIL2 belongs to the Argonaute family of proteins, which function in development and maintenance of germline stem cells. Plays a central role during spermatogenesis by repressing transposable elements and prevent their mobilization, which is essential for the germline integrity. Plays an essential role in meiotic differentiation of spermatocytes, germ cell differentiation and in self-renewal of spermatogonial stem cells. Its presence in oocytes suggests that it may participate in similar functions during oogenesis in females. Indirectly modulate expression of genes such as PDGFRB, SLC2A1, ITGA6, GJA7, THY1, CD9 and STRA8. Inhibits tumor cell growth when re
ImmunogenImmunogen: A synthetic peptide of human PIWIL2 Subcellular Location: Cytoplasm. Present in chromatoid body. Probable component of the meiotic nuage, also named P granule, a germ-cell-specific organelle required to repress transposon during meiosis. Tissue Specificity: Expressed in adult testis and in most tumors. Predicted Cross Reactivity: Pig, Zebrafish, Bovine, Horse, Rabbit, Dog, Chicken, Xenopus Similarity: Pig (100%), Zebrafish (92%), Bovine (100%), Horse (100%), Rabbit (100%), Dog (100%),
Other Names[Cancer/testis antigen 80; CT80; Hiwi like; MILI; Miwi like; Piwi like 2; Piwi-like protein 2; Piwil2; PIWL2_HUMAN]
Gene, Accession #[PIWIL2], Gene ID: 55124, NCBI: NP_001129193.1, UniProt: Q8TC59
Catalog #MBS9607821
Price$240, $280
Order / More InfoPIWIL2 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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