Edit |   |
---|---|
Antigenic Specificity | HLA-G |
Clone | [1E5A10] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2b |
Format | Protein A purified |
Size | 0.06 mL, 0.12 mL, 0.2 mL |
Concentration | 1mg/mL |
Applications | Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Human major histocompatibility complex (MHC) antigens, also referred to as human leukocyte antigens (HLA), are encoded by genes located on the short arm of chromosome 6 (6p21.3). HLA-G is a non-classical MHC class I molecule with multiple immunoregulatory properties. HLA-G exhibits a restricted pattern of expression that includes placental extravillous trophoblasts at the maternal-fetal interface, where it abolishes maternal immune cell activity against fetus and establishes immune tolerance. Aberrant expression of HLA-G has been found in a variety of human neoplastic diseases. It plays an important role in the escape of tumor cells from immunosurveillance. |
Immunogen | Immunogen: Fusion protein of HLA-G Buffer: PBS with 0.02% sodium azide, 50% glycerol, PH7.3 Conjugation: Unconjugated |
Other Names | [HLA 6.0; HLA G; HLA G antigen; HLAG; HLA-G; MHC class I antigen G; MHC G] |
Gene, Accession # | [HLA-G], Gene ID: 3135, NCBI: BC021708, UniProt: P17693 |
Catalog # | MBS2549081 |
Price | $220, $290, $435 |
Order / More Info | HLA-G Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |