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Antigenic Specificity | UBE2K (N-term), 2-30 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse (predicted reactivity: bovine) |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.5 |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This UBE2K antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 2-30 amino acids from the N-terminal region of human UBE2K. The protein encoded by this gene belongs to theubiquitin-conjugating enzyme family. This protein interacts withRING finger proteins, and it can ubiquitinate huntingtin, the geneproduct for Huntington's disease. Known functions for this proteininclude a role in aggregate formation of expanded polyglutamineproteins and the suppression of apoptosis in polyglutaminediseases, a role in the dislocation of newly synthesized MHC classI heavy chains from the endoplasmic reticulum, and involvement infoam cell formation. Multiple transcript variants encoding< |
Immunogen | n/a |
Other Names | [Ubiquitin-conjugating enzyme E2 K; Huntingtin-interacting protein 2; HIP-2; Ubiquitin carrier protein; Ubiquitin-conjugating enzyme E2-25 kDa; Ubiquitin-conjugating enzyme E2(25K); Ubiquitin-conjugating enzyme E2-25K; Ubiquitin-protein ligase; UBE2K; HIP2; LIG] |
Gene, Accession # | [UBE2K], Gene ID: 3093, NCBI: NP_001104582.1, UniProt: P61086 |
Catalog # | MBS9208045 |
Price | $165, $370 |
Order / More Info | UBE2K (N-term), 2-30 Antibody from MYBIOSOURCE INC. |
Product Specific References | Bae, Y., et al. Biochem. Biophys. Res. Commun. 397(4):718-723(2010) Christensen, D.E., et al. Nat. Struct. Mol. Biol. 14(10):941-948(2007) de Pril, R., et al. Mol. Cell. Neurosci. 34(1):10-19(2007) Flierman, D., et al. Proc. Natl. Acad. Sci. U.S.A. 103(31):11589-11594(2006) Yamada, M., et al. J. Biol. Chem. 281(30):20749-20760(2006) |