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Antigenic Specificity | SNCA/Alpha-Synuclein (aa91-102) |
Clone | polyclonal |
Host Species | Goat |
Reactive Species | humanpredicted: mouse, hamster |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 0.05 mg |
Concentration | n/a |
Applications | ELISA (EIA), Immunohistochemistry (IHC) Paraffin, Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Human SNCA/Alpha-Synuclein. This antibody is expected to recognize both reported isoforms (NP_009292.1; NP_000336.1). Reported variants represent identical protein: NP_000336.1, NP_001139527.1, NP_001139526.1. Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major componentof amyloid plaques in the brains of patients with Alzheimer's disease. |
Immunogen | Immunogen: Synthetic peptide C-ATGFVKKDQLGK from an internal region of human SNCA/Alpha-Synuclein (NP 009292.1; NP 000336.1). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Orangutan, Gibbon, Hamster, Lizard (100%); Monkey, Marmoset, Mouse, Rat, Panda, Dog, Rabbit, Porcine, Guinea pig (92%); Tamarin, Elephant, Horse, Turkey, Zebra finch, Chicken (83%). Conjugation: Unconjugated |
Other Names | [Mouse [clone syn211] (IgG1) to Human SNCA/Alpha-Synuclein; SNCA; Alpha-synuclein; PARK4; PD1; Synuclein alpha-140; NACP; PARK1] |
Gene, Accession # | [SNCA], Gene ID: 6622, NCBI: NP_000336.1, UniProt: P37840 |
Catalog # | MBS2401028 |
Price | $530 |
Order / More Info | SNCA/Alpha-Synuclein (aa91-102) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |