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Antigenic Specificity | Phospho-PECAM-1 (Tyr713) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Phospho-PECAM-1 (Tyr713) antibody detects endogenous levels of PECAM-1 only when phosphorylated at Tyrosine 713. Description: PECAM-1 is a cell adhesion molecule expressed on platelets and at endothelial cell intercellular junctions.Function: Cell adhesion molecule which is required for leukocyte transendothelial migration (TEM) under most inflammatory conditions (PubMed:19342684, PubMed:17580308). Tyr-690 plays a critical role in TEM and is required for efficient trafficking of PECAM1 to and from the lateral border recycling compartment (LBRC) and is also essential for the LBRC membrane to be targeted around migrating leukocytes (PubMed:19342684). Trans-homophilic interaction may play a role in endothelial cell-cell adhesi |
Immunogen | Immunogen: A synthesized peptide derived from human PECAM-1 around the phosphorylation site of Tyrosine 713 Subcellular Location: Membrane. Cell junction. Localizes to the lateral border recycling compartment (LBRC) and recycles from the LBRC to the junction in resting endothelial cells and Cell junction. Localizes to the lateral border recycling compartment (LBRC) and recycles from the LBRC to the junction in resting endothelial cells. Tissue Specificity: Expressed on platelets and leukocytes a |
Other Names | [Adhesion molecule; CD31; CD31 antigen; CD31 EndoCAM; EndoCAM; FLJ34100; FLJ58394; GPIIA; GPIIA'; PECA1; PECA1_HUMAN; Pecam 1; PECAM 1 CD31 EndoCAM; PECAM; PECAM-1; Pecam1; Platelet and endothelial cell adhesion molecule 1; Platelet endothelial cell adhesion molecule; Platelet/endothelial cell adhesion molecule 1] |
Gene, Accession # | [PECAM-1], Gene ID: 5175, NCBI: NP_000433.4, UniProt: P16284 |
Catalog # | MBS9600962 |
Price | $240, $280 |
Order / More Info | Phospho-PECAM-1 (Tyr713) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |