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Antigenic Specificity | Nicotinic Acetylcholine Receptor alpha7 |
Clone | polyclonal |
Host Species | Goat |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Immunohistochemistry (IHC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The Nicotinic Acetylcholine Receptors are members of a superfamily of ligand gated ion channels that mediate fast signal transmission at synapses. The Nicotinic Acetylcholine Receptor alpha 7 forms a homo oligomeric channel, displays marked permeability to calcium ions and is a major component of brain nicotinic receptors that are blocked by, and highly sensitive to, alpha bungarotoxin. Once this receptor binds acetylcholine, it undergoes an extensive change in conformation that affects all subunits and leads to opening of an ion conducting channel across the plasma membrane. |
Immunogen | Immunogen: Synthetic peptide: Peptide with sequence KRPGEDKVRPACQHKQ, from the internal region of the protein sequence according to NP_000737.1. |
Other Names | [Neuronal acetylcholine receptor subunit alpha-7; Neuronal acetylcholine receptor subunit alpha-7; CHRNA7-FAM7A fusion protein; CHRNA7 (exons 5-10) and FAM7A (exons A-E) fusion], [CHRFAM7A; CHRNA7; D-10; CHRNA7; NACHRA7; CHRNA7-DR1; NACHRA7] |
Gene, Accession # | Gene ID: 89832, NCBI: P36544.5, UniProt: P36544 |
Catalog # | MBS555913 |
Price | $440 |
Order / More Info | Nicotinic Acetylcholine Receptor alpha7 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |