ITFG2 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | ITFG2 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: ITFG2 antibody detects endogenous levels of total ITFG2. Function: As part of the KICSTOR complex functions in the amino acid-sensing branch of the TORC1 signaling pathway. Recruits, in an amino acid-independent manner, the GATOR1 complex to the lysosomal membranes and allows its interaction with GATOR2 and the RAG GTPases. Functions upstream of the RAG GTPases and is required to negatively regulate mTORC1 signaling in absence of amino acids. In absence of the KICSTOR complex mTORC1 is constitutively localized to the lysosome and activated. The KICSTOR complex is also probably involved in the regulation of mTORC1 by glucose.Subunit Structure: Part of the KICSTOR complex composed of KPTN, ITFG2, C12orf66 and SZT2. SZT2 proba |
| Immunogen | Immunogen: A synthesized peptide derived from human ITFG2 Subcellular Location: Lysosome |
| Other Names | [Integrin alpha FG GAP repeat containing 2; Integrin alpha FG GAP repeat containing protein 2; Integrin-alpha FG-GAP repeat-containing protein 2; ITFG 2; ITFG2; ITFG2_HUMAN; MDS 028; MDS028; OTTHUMP00000161190; RGD1311944; Uncharacterized hematopoietic stem/progenitor cells protein MDS028] |
| Gene, Accession # | [ITFG2], Gene ID: 55846, NCBI: NP_060933.3, UniProt: Q969R8 |
| Catalog # | MBS9609314 |
| Price | $240, $280 |
| Order / More Info | ITFG2 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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