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Antigenic Specificity | MXD3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: MXD3 antibody detects endogenous levels of total MXD3. Function: Transcriptional repressor. Binds with MAX to form a sequence-specific DNA-binding protein complex which recognizes the core sequence 5'-CAC[GA]TG-3'. Antagonizes MYC transcriptional activity by competing for MAX and suppresses MYC dependent cell transformation (By similarity).Subunit Structure: Efficient DNA binding requires dimerization with another bHLH protein. Binds DNA as a heterodimer with MAX. Interacts with SIN3A AND SIN3B. Interacts with RNF17 (By similarity). |
Immunogen | Immunogen: A synthesized peptide derived from human MXD3 Subcellular Location: Nucleus Predicted Cross Reactivity: Pig, Bovine, Horse, Sheep, Rabbit, Dog Similarity: Pig (100%), Bovine (100%), Horse (100%), Sheep (100%), Rabbit (100%), Dog (100%) |
Other Names | [bHLHc13; Class C basic helix-loop-helix protein 13; FLJ35523; Likely ortholog of mouse Max dimerization protein 3; MAD3_HUMAN; MAX dimerization protein 3; Max dimerizer 3; Max-associated protein 3; Max-interacting transcriptional repressor MAD3; MGC2383; mxd3; Myx; OTTHUMP00000223596; OTTHUMP00000223598] |
Gene, Accession # | [MXD3], Gene ID: 83463, NCBI: NP_001136407.1, UniProt: Q9BW11 |
Catalog # | MBS9608480 |
Price | $240, $280 |
Order / More Info | MXD3 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |