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Antigenic Specificity | GNB1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit IgG polyclonal antibody for Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1(GNB1) detection. Background: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 is a protein that in humans is encoded by the GNB1 gene. Heterotrimeric guanine nucleotide-binding proteins (G proteins), which integrate signals between receptors and effector proteins, are composed of an alpha, a beta, and a gamma subunit. These subunits are encoded by families of related genes. This gene encodes a beta subunit. Beta subunits are important regulators of alpha subunits, as well as of certain signal transduction receptors and effectors. This gene uses alternative polyadenylation signals. |
Immunogen | Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human GNB1 (2-42aa SELDQLRQEAEQLKNQIRDARKACADATLSQITNNIDPVGR), identical to the related mouse and rat sequences. |
Other Names | [G protein beta 1 subunit; GBB1; gnb1; P62873; Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1; G protein subunit beta 1], [GNB1; GNB1; MRD42] |
Gene, Accession # | [GNB1], Gene ID: 2782, NCBI: NP_001269467.1, UniProt: P62873 |
Catalog # | MBS178823 |
Price | $315 |
Order / More Info | GNB1 Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Codina J, Stengel D, Woo SL, Birnbaumer L (1986). Beta-subunits of the human liver Gs/Gi signal-transducing proteins and those of bovine retinal rod cell transducin are identical. FEBS Lett. 207 (2): 187-92.2. Yan K, Kalyanaraman V, Gautam N (March 1996). Differential ability to form the G protein betagamma complex among members of the beta and gamma subunit families. J. Biol. Chem. 271 (12): 7141-6. |