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Antigenic Specificity | STAM |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Involved in intracellular signal transduction mediated by cytokines and growth factors. Upon IL-2 and GM-CSL stimulation, it plays a role in signaling leading to DNA synthesis and MYC induction. May also play a role in T-cell development. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with HGS (ESCRT-0 complex). The ESCRT-0 complex binds ubiquitin and acts as sorting machinery that recognizes ubiquitinated receptors and transfers them to further sequential lysosomal sorting/trafficking processes. |
Immunogen | Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 120-210 of human STAM (NP 003464.1). |
Other Names | [STAM1; STAM-1] |
Gene, Accession # | [STAM], Gene ID: 8027, NCBI: Q92783.3, UniProt: Q92783 |
Catalog # | MBS8545345 |
Price | $280 |
Order / More Info | STAM Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |