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Antigenic Specificity | Phospho-SMC1 (S957) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Phospho-SMC1 (S957) Antibody detects endogenous levels of Phospho-SMC1 (S957). Structural maintenance of chromosomes 1 (SMC1) protein is a chromosomal protein member of the cohesin complex that enables sister chromatid cohesion and plays a role in DNA repair. ATM/NBS1-dependent phosphorylation of SMC1 occurs at Ser957 and Ser966 in response to ionizing radiation (IR) as part of the intra-S-phase DNA damage checkpoint. SMC1 phosphorylation is ATM-independent in cells subjected to other forms of DNA damage, including UV light and hydroxyurea treatment. |
Immunogen | Immunogen: A synthesized peptide derived from human Phospho-SMC1 (S957) |
Other Names | [SB1.8/DXS423E protein; SM1A; SMC1A; SMC1L1; SMC1alpha protein; Sb1.8] |
Gene, Accession # | [SMC1], Gene ID: 8243, NCBI: NP_006297.2, UniProt: Q14683 |
Catalog # | MBS4750393 |
Price | $335 |
Order / More Info | Phospho-SMC1 (S957) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |