TLR8 Antibody from MYBIOSOURCE INC.
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|---|---|
| Antigenic Specificity | TLR8 |
| Clone | polyclonal |
| Host Species | n/a |
| Reactive Species | human, rat |
| Isotype | n/a |
| Format | immunogen affinity purified |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Description: Rabbit IgG polyclonal antibody for Toll-like receptor 8(TLR8) detection. Tested with WB in Human;Rat. Background: TLR8 (Toll-like receptor 8) is a protein that in humans is encoded by the TLR8 gene. TLR8 has also been designated as CD288 (cluster of differentiation 288).The TLR8 gene is mapped to Xp22.3-p22.2 by Chuang and Ulevitch (2000) and Du et al. (2000). The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious age |
| Immunogen | Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human TLR8 (881-907aa DAYISYDTKDASVTDWVINELRYHLEE), identical to the related mouse sequence. Ig Type: Rabbit IgG |
| Other Names | [Toll-like receptor 8; CD 288; CD288; CD288 antigen; MGC119599; MGC119600; TLR 8; Tlr8; TLR8_HUMAN; Toll Like Receptor 8; Toll-like receptor 8; toll-like receptor 8], [TLR8; TLR8; CD288] |
| Gene, Accession # | [TLR8], Gene ID: 51311, NCBI: NP_057694.2, UniProt: Q9NR97 |
| Catalog # | MBS178184 |
| Price | $280 |
| Order / More Info | TLR8 Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Chuang, T.-H., Ulevitch, R. J.Cloning and characterization of a sub-family of human Toll-like receptors: hTLR7, hTLR8 and hTLR9.Europ. Cytokine Netw. 11: 372-378, 2000. 2. Kadowaki, N., Ho, S., Antonenko, S., de Waal Malefyt, R., Kastelein, R. A., Bazan, F., Liu, Y.-J.Subsets of human dendritic cell precursors express different Toll-like receptors and respond to different microbial antigens.J. Exp. Med. 194: 863-869, 2001. 3. Peng, G., Guo, Z., Kiniwa, Y., Voo, K., Peng, W., Fu, T., Wang, D. Y., Li, Y., Wang, H. Y., Wang, R.-F.Toll-like receptor 8-mediated reversal of CD4 regulatory T cell function.Science 309: 1380-1384, 2005. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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