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Antigenic Specificity | HLA class II histocompatibility antigen, DR alpha chain |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | caprylic acid ammonium sulfate precipitate |
Size | 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous level of total HLA class II histocompatibility antigen, DR alpha chain polyclonal antibody. Binds peptides derived from antigens that access the endocytic route of antigen presenting cells (APC) and presents them on the cell surface for recognition by the CD4 T-cells. The peptide binding cleft accommodates peptides of 10-30 residues. The peptides presented by MHC class II molecules are generated mostly by degradation of proteins that access the endocytic route, where they are processed by lysosomal proteases and other hydrolases. Exogenous antigens that have been endocytosed by the APC are thus readily available for presentation via MHC II molecules, and for this reason this antigen presentation pathway is us |
Immunogen | Immunogen: Recombinant Human HLA class II histocompatibility antigen, DR alpha chain protein |
Other Names | [MHC class II antigen DRA; HLA-DRA; HLA-DRA1] |
Gene, Accession # | Gene ID: 3122, NCBI: NP_061984.2, UniProt: P01903 |
Catalog # | MBS9415656 |
Price | $320 |
Order / More Info | HLA class II histocompatibility antigen, DR alpha chain Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |