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Antigenic Specificity | PDE11A - N-terminal region |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The 3',5'-cyclic nucleotides cAMP and cGMP function as second messengers in a wide variety of signal transduction pathways. 3',5'-cyclic nucleotide phosphodiesterases (PDEs) catalyze the hydrolysis of cAMP and cGMP to the corresponding 5'-monophosphates and provide a mechanism to downregulate cAMP and cGMP signaling. This gene encodes a member of the PDE protein superfamily. Mutations in this gene are a cause of Cushing disease and adrenocortical hyperplasia. Multiple transcript variants encoding different isoforms have been found for this gene. |
Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PDE11A |
Other Names | [dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A isoform 1; Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A; dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A; phosphodiesterase 11A; cAMP and cGMP phosphodiesterase 11A] |
Gene, Accession # | [PDE11A], Gene ID: 50940, NCBI: NP_001070664.1, UniProt: Q9HCR9 |
Catalog # | MBS3219802 |
Price | $335 |
Order / More Info | PDE11A - N-terminal region Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |