Mouse CD254 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityMouse CD254
Clone[IK22/5]
Host SpeciesRat
Reactive Speciesn/a
IsotypeIgG2a
Formatunconjugated
Size0.25 mg
ConcentrationIgG concentration 0.5mg/ml
ApplicationsFlow cytometry (FC/FACS), Immunohistochemistry-Frozen (IHC-F), Immunoprecipitation (IP), Western Blot (WB), Immunofluorescence (IF)
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DescriptionSpecificity: Rat anti Mouse CD254 antibody, clone IK22/5 recognizes CD254, otherwise known as Receptor activator of nuclear factor kappa B ligand (RANKL) or TNF-related activation-induced cytokine (TRANCE), a member of the tumour necrosis factor ligand superfamily. CD254 is a cytokine that binds osteoprotegerin or RANK and plays an important role in bone metabolism, where it acts as an osteoclast differentiation and activation factor. Overproduction of CD254 is implicated in a range of degenerative bone diseases. CD254 is also expressed by T helper cells and augments the ability of dendritic cells to stimulate naive T cell proliferation. It may play a role in regulating interactions between T cells and dendritic cells and in the regulation
Immunogenn/a
Other Names[Obgl, Rankl, Trance], [Tnfsf11; Tnfsf11; ODF; OPG; OPGL; RANKL; Ly109l; Trance; Opgl; Rankl; Trance; ODF; OPGL; RANKL; TRANCE]
Gene, Accession #[CD254], Gene ID: 21943, NCBI: NP_035743.2, UniProt: O35235
Catalog #MBS219550
Price$430
Order / More InfoMouse CD254 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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