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Antigenic Specificity | Mouse CD254 |
Clone | [IK22/5] |
Host Species | Rat |
Reactive Species | n/a |
Isotype | IgG2a |
Format | unconjugated |
Size | 0.25 mg |
Concentration | IgG concentration 0.5mg/ml |
Applications | Flow cytometry (FC/FACS), Immunohistochemistry-Frozen (IHC-F), Immunoprecipitation (IP), Western Blot (WB), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Rat anti Mouse CD254 antibody, clone IK22/5 recognizes CD254, otherwise known as Receptor activator of nuclear factor kappa B ligand (RANKL) or TNF-related activation-induced cytokine (TRANCE), a member of the tumour necrosis factor ligand superfamily. CD254 is a cytokine that binds osteoprotegerin or RANK and plays an important role in bone metabolism, where it acts as an osteoclast differentiation and activation factor. Overproduction of CD254 is implicated in a range of degenerative bone diseases. CD254 is also expressed by T helper cells and augments the ability of dendritic cells to stimulate naive T cell proliferation. It may play a role in regulating interactions between T cells and dendritic cells and in the regulation |
Immunogen | n/a |
Other Names | [Obgl, Rankl, Trance], [Tnfsf11; Tnfsf11; ODF; OPG; OPGL; RANKL; Ly109l; Trance; Opgl; Rankl; Trance; ODF; OPGL; RANKL; TRANCE] |
Gene, Accession # | [CD254], Gene ID: 21943, NCBI: NP_035743.2, UniProt: O35235 |
Catalog # | MBS219550 |
Price | $430 |
Order / More Info | Mouse CD254 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |