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Antigenic Specificity | SPHK1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | affinity purified |
Size | 0.05 mL, 0.1 mL, 0.2 mL |
Concentration | n/a |
Applications | Western Blot (WB), Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The protein encoded by this gene catalyzes the phosphorylation of sphingosine to form sphingosine1phosphate (S1P), a lipid mediator with both intraand extracellular functions. Intracellularly, S1P regulates proliferation and survival, and extracellularly, it is a ligand for cell surface G proteincoupled receptors. This protein, and its product S1P, play a key role in TNFalpha signaling and the NFkappaB activation pathway important in inflammatory, antiapoptotic, and immune processes. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011] |
Immunogen | Immunogen: A synthetic peptide of human SPHK1 |
Other Names | [SPHK1; SPHK1; SPHK; Sphingosine kinase 1;], [SPHK1; SPHK1; SPHK; SPHK; SPK; SK 1; SPK 1] |
Gene, Accession # | Gene ID: 8877, NCBI: NP_001136073.1, UniProt: Q9NYA1 |
Catalog # | MBS125401 |
Price | $200, $275, $430 |
Order / More Info | SPHK1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |