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Antigenic Specificity | Lymphotactin Picoband |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse, rat |
Isotype | n/a |
Format | unconjugated |
Size | 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Description: Chemokine (C motif) ligand (XCL1) is a small cytokine belonging to the XC chemokine family that is also known as lymphotactin. Muller et al. (1995) mapped the gene to chromosome 1q23 by FISH. The sequence of the deduced 114-amino acid protein is most homologous to the CC chemokines CCL8 and CCL3. It is found in high levels in spleen, thymus, intestine and peripheral blood leukocytes, and at lower levels in lung, prostate gland and ovary. XCL1 induces the migration of cells expressing XCR1.Protein Function: Chemotactic activity for lymphocytes but not for monocytes or neutrophils. In thymus, mediates medullary accumulation of thymic dendritic cells and contributes to regulatoy T cell development, playing a role in self-toler |
Immunogen | Immunogen: E Coli-derived mouse Lymphotactin recombinant protein (Position: V22-G114). Subcellular Localization: Secreted. Tissue Specificity: Expressed in activated CD8( ) T cells. In the thymus, expressed by medullary thymic epithelial cells. |
Other Names | [Lymphotactin; C motif chemokine 1; Cytokine SCM-1; Lymphotaxin; Small-inducible cytokine C1; Xcl1; Lptn; Ltn; Scyc1] |
Gene, Accession # | [Xcl1], Gene ID: 16963, NCBI: NP_032536.1, UniProt: P47993 |
Catalog # | MBS1750878 |
Price | $280 |
Order / More Info | Lymphotactin Picoband Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |