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Antigenic Specificity | Maf |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total Maf protein. Acts as a transcriptional activator or repressor. Involved in embryonic lens fiber cell development. Recruits the transcriptional coactivators CREBBP and/or EP300 to crystallin promoters leading to up-regulation of crystallin gene during lens fiber cell differentiation. Activates the expression of IL4 in T helper 2 (Th2) cells. Increases T-cell susceptibility to apoptosis by interacting with MYB and decreasing BCL2 expression. Together with PAX6, transactivates strongly the glucagon gene promoter through the G1 element. Activates transcription of the CD13 proximal promoter in endothelial cells. Represses transcription of the CD13 promoter in early stages of myelopoiesis by affecti |
Immunogen | Immunogen Type: Peptide Immunogen Description: Synthesized peptide derived from Internal of human Maf. |
Other Names | [Transcription factor Maf; Proto-oncogene c-maf; MAF] |
Gene, Accession # | [Maf], Gene ID: 4094, NCBI: NP_001026974.1, UniProt: O75444 |
Catalog # | MBS9407294 |
Price | $200, $255 |
Order / More Info | Maf Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |