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Antigenic Specificity | IL-1RAcP |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This polyclonal antibody has no cross activity to other members in the IL-1 receptor family. IL-1RAcP Antibody: The pro-inflammatory cytokine IL-1 induced cellular response requires two subunits of its receptor, IL-1 receptor I (IL-1RI) and IL-1 receptor accessory protein (IL-1RAcP). IL-1RAcP forms a complex with IL-1RI in response to IL-1 treatment. The IL-1 receptor-associated kinase (IRAK), which mediates activation of NF-κB inducing kinae (NIK) and of NF-κB, recruits to the IL-1R complex through IL-1RAcP. IL-1 activation of stress-activated protein kinase and of acid sphingomyelinase also requires IL-1RAcP. Like IL-1RI, IL-1RAcP subunit is essential for IL-1 mediated cellular response. IL-1RAcP is expressed in many tissues. |
Immunogen | Immunogen: IL-1RAcP antibody was raised against a 16 amino acid peptide near the carboxy terminus of human IL-1RAcP. Buffer: IL-1RAcP Antibody is supplied in PBS containing 0.02% sodium azide. |
Other Names | [IL-1RAcP; IL1R3; C3orf13; IL-1RAcP; IL1R3; Interleukin-1 receptor accessory protein; Interleukin-1 receptor 3; IL-1 receptor accessory protein; interleukin 1 receptor accessory protein], [IL1RAP; IL1RAP; IL1R3; C3orf13; IL-1RAcP; C3orf13; IL1R3; IL-1 receptor accessory protein; IL-1RAcP; IL-1R-3; IL-1R3] |
Gene, Accession # | [IL1RAP], Gene ID: 3556, NCBI: AF029213, UniProt: Q9NPH3 |
Catalog # | MBS150099 |
Price | $375 |
Order / More Info | IL-1RAcP Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |