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Antigenic Specificity | SYT1 |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | affinity purified |
Size | 0.05 mL, 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: SYT1 antibody detects endogenous levels of total SYT1. Description: SYT1: synaptotagmin I. The synaptotagmins are integral membrane proteins of synaptic vesicles thought to serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis. Calcium binding to synaptotagmin I participates in triggering neurotransmitter release at the synapse.Function: May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone. A Ca2+-dependent interaction between synaptotagmin and putative receptors for activated protein kinase C has |
Immunogen | Immunogen: Purified recombinant fragment of human SYT1 expressed in E. Coli Subcellular Location: Cytoplasmic Vesicle > Secretory Vesicle > Synaptic Vesicle Membrane. Cytoplasmic Vesicle > Secretory Vesicle > Chromaffin Granule Membrane. Cytoplasm. Synaptic vesicles and chromaffin granules. Tissue Specificity: Expressed in melanocytes (PubMed:23999003). |
Other Names | [DKFZp781D2042; FLJ42519; p65; SVP65; Synaptotagmin 2; Synaptotagmin I; Synaptotagmin II; Synaptotagmin-1; SYT; Syt1; SYT1_HUMAN; Syt2; SytI; Synaptotagmin 2; Synaptotagmin II; Synaptotagmin-2; Synaptotagmin2; SynaptotagminII; SYT 2; Syt II; Syt2; SYT2_HUMAN; SytII] |
Gene, Accession # | [SYT1], Gene ID: 6857, NCBI: NP_001129277.1, UniProt: P21579 |
Catalog # | MBS9602735 |
Price | $235, $295, $370 |
Order / More Info | SYT1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |