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Antigenic Specificity | Crystallin-alphaC |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous Crystallin-alphaC protein. The protein encoded by HSPB8 (heat shock protein family B (small) member 8) belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule. The expression of HSPB8 in induced by estrogen in estrogen receptor-positive breast cancer cells, and this protein also functions as a chaperone in association with Bag3, a stimulator of macroautophagy. Thus, HSPB8 appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in HSPB8 have been associated with different neuromuscular diseases, including Charcot-Marie-Tooth disease. |
Immunogen | Immunogen: Recombinant Protein |
Other Names | [Rabbit Crystallin-alphaC] |
Gene, Accession # | Gene ID: 26353, NCBI: Q9UJY1.1, UniProt: Q9UJY1 |
Catalog # | MBS9707886 |
Price | $130, $220, $325 |
Order / More Info | Crystallin-alphaC Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |