Crystallin-alphaC Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityCrystallin-alphaC
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatimmunogen affinity purified
Size0.03 mL, 0.1 mL, 0.2 mL
Concentration1 mg/ml
ApplicationsWestern Blot (WB)
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DescriptionThe antibody detects endogenous Crystallin-alphaC protein. The protein encoded by HSPB8 (heat shock protein family B (small) member 8) belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule. The expression of HSPB8 in induced by estrogen in estrogen receptor-positive breast cancer cells, and this protein also functions as a chaperone in association with Bag3, a stimulator of macroautophagy. Thus, HSPB8 appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in HSPB8 have been associated with different neuromuscular diseases, including Charcot-Marie-Tooth disease.
ImmunogenImmunogen: Recombinant Protein
Other Names[Rabbit Crystallin-alphaC]
Gene, Accession #Gene ID: 26353, NCBI: Q9UJY1.1, UniProt: Q9UJY1
Catalog #MBS9707886
Price$130, $220, $325
Order / More InfoCrystallin-alphaC Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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