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Antigenic Specificity | ICAM-1, Human |
Clone | 100 ig 206 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | unconjugated |
Size | 0.1 mg |
Concentration | n/a |
Applications | F, Flow Cytometry (FC/FACS), Immunoassay (IA), Immunofluorescence (IF), Immunoprecipitation (IP), P |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Product Description: The monoclonal HM.2 antibody reacts with the 90 kD glycoprotein Intracellular Adhesion Molecule-1 (ICAM-1). The adhesion molecule ICAM-1 belongs to the immunoglobulin superfamily, C2 subset; it is a ligand for the Integrins LFA-1 and MAC-1 and for CD43. ICAM-1 is an essential component in many immune-related processes. ICAM-1 links with receptors of the integrin family, thereby mediating cell-cell interactions and allowing for signal transduction. ICAM-1 interacts specifically with its receptors to induce a reversible adhesion interaction. For processes like T cell activation and leucocyte recruitment, normal immune function relies on ICAM-1. Therefore, it is understandable that alterations in ICAM-1 structure or expres |
Immunogen | n/a |
Other Names | [ICAM-1, CD54], [ICAM1; ICAM1; BB2; CD54; P3.58; ICAM-1] |
Gene, Accession # | [ICAM-1], Gene ID: 3383, NCBI: NP_000192.2 |
Catalog # | MBS584054 |
Price | $420 |
Order / More Info | ICAM-1, Human Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. van de Stolpe, A et al; Intercellular adhesion molecule-1. J Mol Med 1996; 74:13 2. Sligh. J et al; Inflammatory and immune responses are impaired in mice deficint in intercellular adehesion molecule 1. PNAS 1993; 90: 8529 |