HIF1 alpha (Hypoxia-Inducible Factor 1-alpha) Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-HIF1 alpha (Hypoxia-Inducible Factor 1-alpha) antibody, protein, ELISA kits.
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| Antigenic Specificity | HIF1 alpha (Hypoxia-Inducible Factor 1-alpha) |
| Clone | [ESEE122] |
| Host Species | Mouse |
| Reactive Species | human, cow, dog, mouse, rat |
| Isotype | IgG1, kappa |
| Format | purified |
| Size | 0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml) |
| Concentration | n/a |
| Applications | ELISA (EIA), Flow Cytometry (FC/FACS), Immunofluorescence (IF) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: HIF1 (hypoxia-inducible factor 1), a heterodimeric transcription factor complex central to cellular response to hypoxia, consists of two subunits (HIF-1 alpha and HIF-1 beta) which are basic helix-loop-helix proteins of the PAS (Per, ARNT, Sim) family. Expression of HIF-1 alpha protein is regulated by cellular oxygen level alterations as well as in oxygen-independent manner via different cytokines (through the PI3K-AKT-mTOR pathway), growth factors, oncogenic activation, or loss of tumor suppressor function etc. In normoxic cells, HIF-1 alpha is proline hydroxylated leading to a conformational change that promotes its binding to the VLH (von Hippel Lindau) protein E3 ligase complex; ubiquitination and followed by rapid proteaso |
| Immunogen | Immunogen: GST-human HIF-1A amino acids 329-530 fusion protein |
| Other Names | [ARNT-interacting protein; Basic-helix-loop-helix-PAS protein MOP1; Class E basic helix-loop-helix protein 78 (bHLHe78); Member of PAS superfamily 1 (MOP1); PAS domain-containing protein 8 (PASD8)] |
| Gene, Accession # | [HIF1A], Gene ID: 3091, NCBI: NP_001521.1, UniProt: Q16665 |
| Catalog # | MBS4380979 |
| Price | $190, $340, $340 |
| Order / More Info | HIF1 alpha (Hypoxia-Inducible Factor 1-alpha) Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Talks et al. 2000. Am J Pathol. 157(2):411-21. 2. Wiesener et al. 1998. Blood. 92(7):2260-8. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
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