SSeCKS - myristylated (PKC) substrate Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | SSeCKS - myristylated (PKC) substrate |
| Clone | polyclonal |
| Host Species | Sheep |
| Reactive Species | rat |
| Isotype | n/a |
| Format | ammonium sulfate precipitate |
| Size | 0.25 mg |
| Concentration | n/a |
| Applications | Western Blot (WB), Immunoprecipitation (IP), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Activation of protein kinase C is a key signal transduction event in mesangial cell dedifferentiation and proliferation, yet little is known about downstream substrates or their roles in normal or diseased states. SSeCKS, a novel protein kinase C substrate originally isolated as a src-suppressed negative mitogenic regulator in fibroblasts, controls actinbased cytoskeletal architecture and scaffolds key signaling kinases such as protein kinase C and protein kinase A. Activation of protein kinase C is a key signal transduction event in mesangial cell dedifferentiation. A role for SSeCKS, a PKA/PKC scaffolding protein, has been implicated during the process of spermiogenesis and in the actin-based stellate morphology of mesangial cells |
| Immunogen | Immunogen: Recombinant protein corresponding to amino acids 620-1596 of the SSeCKS protein. |
| Other Names | [SSeCKS; A-kinase anchor protein 12; AKAP12; src-suppressed C kinase substrate], [Akap12; 322] |
| Gene, Accession # | [SSeCKS], NCBI: Q62766, UniProt: Q62766 |
| Catalog # | MBS395513 |
| Price | $340 |
| Order / More Info | SSeCKS - myristylated (PKC) substrate Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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