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Antigenic Specificity | CD70 (Center), 72-101 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.5 |
Applications | Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This CD70 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 72-101 amino acids from the Central region of human CD70. The protein encoded by this gene is a cytokine thatbelongs to the tumor necrosis factor (TNF) ligand family. Thiscytokine is a ligand for TNFRSF27/CD27. It is a surface antigen onactivated, but not on resting, T and B lymphocytes. It inducesproliferation of costimulated T cells, enhances the generation ofcytolytic T cells, and contributes to T cell activation. Thiscytokine is also reported to play a role in regulating B-cellactivation, cytotoxic function of natural killer cells, andimmunoglobulin sythesis. |
Immunogen | n/a |
Other Names | [CD70 antigen; CD27 ligand; CD27-L; Tumor necrosis factor ligand superfamily member 7; CD70; CD70; CD27L; CD27LG; TNFSF7] |
Gene, Accession # | [CD70], Gene ID: 970, NCBI: NP_001243.1, UniProt: P32970 |
Catalog # | MBS9215214 |
Price | $165, $370 |
Order / More Info | CD70 (Center), 72-101 Antibody from MYBIOSOURCE INC. |
Product Specific References | Arimoto-Miyamoto, K., et al. Immunology 130(1):137-149(2010) Shaw, J., et al. Blood 115(15):3051-3057(2010) Yu, S.E., et al. Mol. Cells 29(2):217-221(2010) Kozlowska, A., et al. J. Rheumatol. 37(1):53-59(2010) Johnatty, S.E., et al. PLoS Genet. 6 (7), E1001016 (2010) : |