Edit |   |
---|---|
Antigenic Specificity | Human BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | n/a |
Applications | ELISA (EIA), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Induces apoptosis. Interacts with viral and cellular anti-apoptosis proteins. Can overcome the suppressors BCL-2 and BCL-XL, although high levels of BCL-XL expression will inhibit apoptosis. Inhibits apoptosis induced by BNIP3. Involved in mitochondrial quality control via its interaction with SPATA18/MIEAP: in response to mitochondrial damage, participates to mitochondrial protein catabolic process (also named MALM) leading to the degradation of damaged proteins inside mitochondria. The physical interaction of SPATA18/MIEAP, BNIP3 and BNIP3L/NIX at the mitochondrial outer membrane regulates the opening of a pore in the mitochondrial double membrane in order to mediate the translocation of lysosomal proteins from the cytoplasm to the mitoch |
Immunogen | Immunogen: Recombinant human BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like protein(1-187aa) Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-5860 / sc-5863 / sc-28240 |
Other Names | [Adenovirus E1B19K-binding protein B5; BCL2/adenovirus E1B 19 kDa protein-interacting protein 3A; NIP3-like protein X; NIP3L; BNIP3L; BNIP3A; BNIP3H; NIX], [BNIP3L; BNIP3L; NIX; BNIP3a; BNIP3A; BNIP3H; NIX; NIP3L] |
Gene, Accession # | [BNIP3L], Gene ID: 665, NCBI: NP_004322.1, UniProt: O60238 |
Catalog # | MBS1494300 |
Price | $120, $160 |
Order / More Info | Human BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |