RNAse H2A Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | RNAse H2A |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mg |
| Concentration | 1 mg/mL |
| Applications | ELISA (EIA), Western Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | RNAse H2A Antibody: Ribonucleases (RNAses) H are enzymes that hydrolyze the RNA strands of RNA/DNA hybrids. The major role of these enzymes is to remove the RNA strand from the RNA/DNA hybrids that form during DNA replication and repair. RNAse H2 is made up of three subunits; all three are required for RNAse activity. Recent evidence has demonstrated that mutations in RNAse H2A or any of the other subunits result in Aicardi-Goutieres syndrome (AGS), a neurological disorder with similar symptoms to viral brain infections including high levels of IFN-alpha in the cerebral spinal fluid. Similar conditions are observed with mutations in TREX1, a single-stranded DNA exonuclease, suggesting that RNAse H2 and TREX1 may have similar roles, and that |
| Immunogen | Immunogen: RNAse H2A antibody was raised against a 17 amino acid synthetic peptide near the center of human RNAse H2A. Buffer: RNAse H2A Antibody is supplied in PBS containing 0.02% sodium azide. |
| Other Names | [RNAse H2A; AGS4; JUNB; RNHL; RNHIA; RNASEHI; Ribonuclease H2 subunit A; Aicardi-Goutieres syndrome 4 protein; RNase H2 subunit A; ribonuclease H2, subunit A], [RNASEH2A; RNASEH2A; AGS4; JUNB; RNHL; RNHIA; RNASEHI; RNASEHI; RNHIA; RNase H2 subunit A; AGS4; RNase HI large subunit] |
| Gene, Accession # | [RNASEH2A], Gene ID: 10535, NCBI: O75792.2, UniProt: O75792 |
| Catalog # | MBS151275 |
| Price | $375 |
| Order / More Info | RNAse H2A Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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