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Antigenic Specificity | SPG20 (N-term), 18-45 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human (predicted reactivity: bovine, mouse) |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.3 |
Applications | Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This SPG20 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 18-45 amino acids from the N-terminal region of human SPG20. SPG20 is a protein containing a MIT (Microtubule Interacting and Trafficking molecule) domain, and is implicated in regulating endosomal trafficking and mitochondria function. The protein localizes to mitochondria and partially co-localizes with microtubules. Stimulation with epidermal growth factor (EGF) results in protein translocation to the plasma membrane, and the protein functions in the degradation and intracellular trafficking of EGF receptor. |
Immunogen | n/a |
Other Names | [Spartin; Spastic paraplegia 20 protein; Trans-activated by hepatitis C virus core protein 1; SPG20; KIAA0610; TAHCCP1] |
Gene, Accession # | [SPG20], Gene ID: 23111, NCBI: NP_001135766.1, UniProt: Q8N0X7 |
Catalog # | MBS9201810 |
Price | $165, $370 |
Order / More Info | SPG20 (N-term), 18-45 Antibody from MYBIOSOURCE INC. |
Product Specific References | Milewska,M., et.al., J. Neurochem. 111 (4), 1022-1030 (2009); Edwards,T.L., et.al., Biochem. J. 423 (1), 31-39 (2009). |