Human Factor VIII Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-Human Factor VIII antibody, protein, ELISA kits.
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| Antigenic Specificity | Human Factor VIII |
| Clone | polyclonal |
| Host Species | Sheep |
| Reactive Species | n/a |
| Isotype | n/a |
| Format | IgG fraction |
| Size | 10 mg |
| Concentration | IgG concentration is mg/ml, determined by absorbance using an extinction coefficient (E1%280) of 13.4. |
| Applications | n/a |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This antibody is specific for F.VIII as demonstrated by immunoelectrophoresis and ELISA. Factor VIII (formerly referred to as antihemophilic globulin and Factor VIII:C) is a large glycoprotein (320 kDa) that circulates in plasma at approximately 200 ng/ml. Synthesized in the liver, the majority of Factor VIII is cleaved during expression, resulting in a heterogeneous mixture of partially cleaved forms of F.VIII ranging in size from 200-280 kDa. The F.VIII is stabilized by association with von Willebrand Factor to form a F.VIII-vWF complex required for the normal survival of F.VIII in vivo (t1/2 of 8-12 hours). F.VIII is a pro-cofactor that is activated through limited proteolysis by thrombin. In this process F.VIIIa dissociates from vWF to |
| Immunogen | Immunogen: Human F.VIII (F.VIII:C) purified from concentrate. |
| Other Names | [Factor VIII:C, human], [FVIII] |
| Gene, Accession # | NCBI: AAD15005.1 |
| Catalog # | MBS512051 |
| Price | $285 |
| Order / More Info | Human Factor VIII Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Lollar P, Fay PJ, Fass DN; Factor VIII and Factor VIIIa. Methods in Enzymology, 222, pg 122, 1993. 2. Hoyer, LW, Wyshock EG, Colman RW, in Hemostasis and Thrombosis, 3rd Edition, eds. RW Colman, J Hirsh, VJ Marder and EW Salzman, pp. 109-133, J.B. Lippincott Co., Philadelphia, 1994. 3. Pittman DD, Kaufman RJ. Structure-Function Relationships of Factor VIII Elucidated through Recombinant DNA Technology. Thromb. Haemostas. 61:161-165, 1989. |
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MYBIOSOURCE INC.
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