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Antigenic Specificity | ACVRL1 (N-term) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human (predicted reactivity: bovine) |
Isotype | n/a |
Format | purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.5 |
Applications | Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This ACVRL1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 11-44amino acids from the N-terminal region of human ACVRL1. Type I receptor for TGF-beta family ligands BMP9/GDF2 and BMP10 and important regulator of normal blood vessel development. On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. May bind activin as well. |
Immunogen | n/a |
Other Names | [Serine/threonine-protein kinase receptor R3; SKR3; Activin receptor-like kinase 1; ALK-1; TGF-B superfamily receptor type I; TSR-I; ACVRL1; ACVRLK1; ALK1] |
Gene, Accession # | [ACVRL1], Gene ID: 94, NCBI: NP_000011.2, UniProt: P37023 |
Catalog # | MBS9206478 |
Price | $165, $370 |
Order / More Info | ACVRL1 (N-term) Antibody from MYBIOSOURCE INC. |
Product Specific References | ten Dijke P.,et al.Oncogene 8:2879-2887(1993). Attisano L.,et al.Cell 75:671-680(1993). Berg J.N.,et al.Am. J. Hum. Genet. 61:60-67(1997). Scherer S.E.,et al.Nature 440:346-351(2006). Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases. |