ACVRL1 (N-term) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityACVRL1 (N-term)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman (predicted reactivity: bovine)
Isotypen/a
Formatpurified
Size0.08 mL, 0.4 mL
Concentrationvial concentration: 0.5
ApplicationsWestern Blot (WB), ELISA (EIA), Immunohistochemistry (IHC)
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DescriptionThis ACVRL1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 11-44amino acids from the N-terminal region of human ACVRL1. Type I receptor for TGF-beta family ligands BMP9/GDF2 and BMP10 and important regulator of normal blood vessel development. On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. May bind activin as well.
Immunogenn/a
Other Names[Serine/threonine-protein kinase receptor R3; SKR3; Activin receptor-like kinase 1; ALK-1; TGF-B superfamily receptor type I; TSR-I; ACVRL1; ACVRLK1; ALK1]
Gene, Accession #[ACVRL1], Gene ID: 94, NCBI: NP_000011.2, UniProt: P37023
Catalog #MBS9206478
Price$165, $370
Order / More InfoACVRL1 (N-term) Antibody from MYBIOSOURCE INC.
Product Specific Referencesten Dijke P.,et al.Oncogene 8:2879-2887(1993). Attisano L.,et al.Cell 75:671-680(1993). Berg J.N.,et al.Am. J. Hum. Genet. 61:60-67(1997). Scherer S.E.,et al.Nature 440:346-351(2006). Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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