Edit |   |
---|---|
Antigenic Specificity | YEATS2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: YEATS2 antibody detects endogenous levels of total YEATS2. Function: Chromatin reader component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4. YEATS2 specifically recognizes and binds histone H3 crotonylated at 'Lys-27' (H3K27cr) (PubMed:27103431). Crotonylation marks active promoters and enhancers and confers resistance to transcriptional repressors (PubMed:27103431).Subunit Structure: Component of the ADA2A-containing complex (ATAC), composed of KAT14, KAT2A, TADA2L, TADA3L, ZZ3, MBIP, WDR5, YEATS2, SGF29 and DR1.Similarity: The YEATS domain specifically recognizes and binds crotonylated histones. |
Immunogen | Immunogen: A synthesized peptide derived from human YEATS2 Subcellular Location: Nucleus |
Other Names | [FLJ10201; FLJ12841; FLJ13308; FLJ33401; FLJ34335; KIAA1197; YEATS domain containing 2; YEATS domain-containing protein 2; Yeats2; YETS2_HUMAN] |
Gene, Accession # | [YEATS2], Gene ID: 55689, NCBI: NP_060493.3, UniProt: Q9ULM3 |
Catalog # | MBS9602276 |
Price | $240, $280 |
Order / More Info | YEATS2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |