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Antigenic Specificity | PRKAA1 |
Clone | [167CT22.1.6] |
Host Species | Mouse |
Reactive Species | human (predicted reactivity: rat) |
Isotype | IgG1,K |
Format | unconjugated |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.5 |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This PRKAA1 monoclonal antibody is generated from mouse immunized with PRKAA1 recombinant protein. Responsible for the regulation of fatty acid synthesis by phosphorylation of acetyl-CoA carboxylase. It also regulates cholesterol synthesis via phosphorylation and inactivation of hormone-sensitive lipase and hydroxymethylglutaryl-CoA reductase. Appears to act as a metabolic stress-sensing protein kinase switching off biosynthetic pathways when cellular ATP levels are depleted and when 5'-AMP rises in response to fuel limitation and/or hypoxia. This is a catalytic subunit. |
Immunogen | n/a |
Other Names | [5'-AMP-activated protein kinase catalytic subunit alpha-1; AMPK subunit alpha-1; Acetyl-CoA carboxylase kinase; ACACA kinase; Hydroxymethylglutaryl-CoA reductase kinase; HMGCR kinase; Tau-protein kinase PRKAA1; PRKAA1; AMPK1] |
Gene, Accession # | [PRKAA1], Gene ID: 5562, NCBI: NP_006242.5, UniProt: Q13131 |
Catalog # | MBS9200091 |
Price | $165, $370 |
Order / More Info | PRKAA1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |