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Antigenic Specificity | IL4R |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.1 mL |
Concentration | 1.2 mg/mL |
Applications | Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total IL4R protein. This gene encodes the alpha chain of the interleukin-4 receptor, a type I transmembrane protein that can bind interleukin 4 and interleukin 13 to regulate IgE production. The encoded protein also can bind interleukin 4 to promote differentiation of Th2 cells. A soluble form of the encoded protein can be produced by proteolysis of the membrane-bound protein, and this soluble form can inhibit IL4-mediated cell proliferation and IL5 upregulation by T-cells. Allelic variations in this gene have been associated with atopy, a condition that can manifest itself as allergic rhinitis, sinusitus, asthma, or eczema. Polymorphisms in this gene are also associated with resistance to human imm |
Immunogen | Immunogen: Synthetic peptide of human IL4R Immunogen Type: Peptide |
Other Names | [CD124; IL4RA; IL-4RA] |
Gene, Accession # | [IL4R], Gene ID: 3566, NCBI: NP_000409.1, UniProt: P24394 |
Catalog # | MBS9430635 |
Price | $255 |
Order / More Info | IL4R Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |