IL4R Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityIL4R
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatantigen affinity purified
Size0.1 mL
Concentration1.2 mg/mL
ApplicationsImmunohistochemistry (IHC)
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DescriptionThe antibody detects endogenous levels of total IL4R protein. This gene encodes the alpha chain of the interleukin-4 receptor, a type I transmembrane protein that can bind interleukin 4 and interleukin 13 to regulate IgE production. The encoded protein also can bind interleukin 4 to promote differentiation of Th2 cells. A soluble form of the encoded protein can be produced by proteolysis of the membrane-bound protein, and this soluble form can inhibit IL4-mediated cell proliferation and IL5 upregulation by T-cells. Allelic variations in this gene have been associated with atopy, a condition that can manifest itself as allergic rhinitis, sinusitus, asthma, or eczema. Polymorphisms in this gene are also associated with resistance to human imm
ImmunogenImmunogen: Synthetic peptide of human IL4R Immunogen Type: Peptide
Other Names[CD124; IL4RA; IL-4RA]
Gene, Accession #[IL4R], Gene ID: 3566, NCBI: NP_000409.1, UniProt: P24394
Catalog #MBS9430635
Price$255
Order / More InfoIL4R Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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