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Antigenic Specificity | NUDT1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: NUDT1 antibody detects endogenous levels of total NUDT1. Description: Misincorporation of oxidized nucleoside triphosphates into DNA/RNA during replication and transcription can cause mutations that may result in carcinogenesis or neurodegeneration. The protein encoded by this gene is an enzyme that hydrolyzes oxidized purine nucleoside triphosphates, such as 8-oxo-dGTP, 8-oxo-dATP, 2-hydroxy-dATP, and 2-hydroxy rATP, to monophosphates, thereby preventing misincorporation. The encoded protein is localized mainly in the cytoplasm, with some in the mitochondria, suggesting that it is involved in the sanitization of nucleotide pools both for nuclear and mitochondrial genomes. Several alternatively spliced transcript variants, some |
Immunogen | Immunogen: A synthesized peptide derived from human NUDT1 Subcellular Location: Cytoplasm. Mitochondrion Matrix and Cytoplasm. Mitochondrion Matrix. Nucleus. Mostly present in cytoplasm. Variant Met-124 has decreased efficiency in translocation to mitochondria. Tissue Specificity: Widely expressed with highest expression in thymus, testis, embryo and proliferating blood lymphocytes. Predicted Cross Reactivity: Pig, Zebrafish, Bovine, Horse, Sheep, Dog, Xenopus Similarity: Pig (100%), Zebrafish ( |
Other Names | [2-hydroxy-dATP diphosphatase; 7 8 dihydro 8 oxoguanine triphosphatase; 7; 8 oxo 7 8 dihydrodeoxyguanosine triphosphatase; 8 oxo 7 8 dihydroguanosine triphosphatase; 8 oxo dGTPase; 8-dihydro-8-oxoguanine triphosphatase; 8-oxo-dGTPase; 8ODP_HUMAN; MTH 1; MTH1; MutT human homolog 1; Nucleoside diphosphate linked moiety X motif 1; Nucleoside diphosphate linked moiety X type motif 1; Nucleoside diphosphate-linked moiety X motif 1; Nudix (nucleoside diphosphate linked moiety X) type motif 1; Nudix hydrolase 1; Nudix motif 1; Nudix type motif 1; NUDT 1; Nudt1] |
Gene, Accession # | [NUDT1], Gene ID: 4521, NCBI: NP_002443.3, UniProt: P36639 |
Catalog # | MBS9607996 |
Price | $240, $280 |
Order / More Info | NUDT1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |