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Antigenic Specificity | CD46 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mg |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Western blot analysis of extracts of various cell lines, using CD46 antibody. Immunohistochemistry of paraffin-embedded human kidney using CD46 antibody at dilution of 1:200 (200x lens). Immunohistochemistry of paraffin-embedded rat lung using CD46 antibody at dilution of 1:200 (200x lens). Immunofluorescence analysis of HepG2 cell using CD46 antibody. Blue: DAPI for nuclear staining. CD46 is a type I membrane protein and a regulatory part of the complement system. This protein has cofactor activity for inactivation of complement components C3b and C4b by serum factor I, which protects the host cell from damage by complement. In addition, CD46 can act as a receptor for the Edmonston strain of measles virus, human herpesvirus-6, |
Immunogen | Immunogen: Recombinant protein of human CD46 |
Other Names | [CD46; Membrane cofactor protein; membrane cofactor protein; CD46 molecule; TLX; Trophoblast leukocyte common antigen; CD_antigen: CD46], [CD46; CD46; MCP; TLX; AHUS2; MIC10; TRA2.10; MCP; MIC10] |
Gene, Accession # | [CD46], Gene ID: 4179, NCBI: BAA12224.1 |
Catalog # | MBS419752 |
Price | $385 |
Order / More Info | CD46 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |