Mouse Fgfr4 (Center) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityMouse Fgfr4 (Center)
Clonepolyclonal
Host SpeciesRabbit
Reactive Speciesmouse, rat
Isotypen/a
Formatpurified
Size0.08 mL
Concentrationvial concentration: 0.5
ApplicationsWestern Blot (WB), ELISA (EIA)
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DescriptionThis Mouse Fgfr4 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 448-482 amino acids from the Central region of Mouse Fgfr4. Tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays a role in the regulation of cell proliferation, differentiation and migration, and in regulation of lipid metabolism, bile acid biosynthesis, glucose uptake, vitamin D metabolism and phosphate homeostasis. Required for normal down-regulation of the expression of CYP7A1, the rate-limiting enzyme in bile acid synthesis, in response to FGF19. Phosphorylates PLCG1 and FRS2. Ligand binding leads to the activation of several signaling cascades. Activation of PLCG1 leads to the prod
Immunogenn/a
Other Names[Fibroblast growth factor receptor 4; FGFR-4; Protein-tyrosine kinase receptor MPK-11; CD334; Fgfr4; Fgfr-4; Mpk-11]
Gene, Accession #[Fgfr4], Gene ID: 14186, NCBI: NP_032037.2, UniProt: Q03142
Catalog #MBS9205497
Price$150
Order / More InfoMouse Fgfr4 (Center) Antibody from MYBIOSOURCE INC.
Product Specific ReferencesStark K.L.,et al.Development 113:641-651(1991). Kwiatkowski B.A.,et al.J. Cell. Physiol. 215:803-817(2008). Carninci P.,et al.Science 309:1559-1563(2005). Gilardi-Hebenstreit P.,et al.Oncogene 7:2499-2506(1992). Weinstein M.,et al.Development 125:3615-3623(1998).
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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