MECR Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityMECR
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatpeptide affinity purified
Size0.1 mg
Concentration1 mg/mL
ApplicationsELISA (EIA), Western Blot (WB)
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DescriptionSpecificity: At least two isoforms of MECR are known to exist; this antibody will detect both isoforms. MECR Antibody: The mitochondrial trans-2-enoyl-CoA reductase (MECR), was initially identified as nuclear receptor-binding factor 1 (NRBF1), which can interact with a multitude of nuclear hormone receptors in the presence of the respective ligands. MECR has been shown to be part of the mitochondrial fatty acid synthesis (FAS II) system and to catalyze the NAPDH-dependent reduction of 2-enoyl thioesters, generating saturated acyl-groups. Overexpression of this gene in transgenic mice can lead to cardiac abnormalities, suggesting that inappropriate expression of genes of FAS II can result in the development of hereditary cardiomyopathy.
ImmunogenImmunogen: Rabbit polyclonal MECR antibody was raised against a 15 amino acid peptide near the carboxy terminus of human MECR. Buffer: MECR Antibody is supplied in PBS containing 0.02% sodium azide.
Other Names[MECR; NRBF1; CGI-63; FASN2B; NBRF1; Trans-2-enoyl-CoA reductase; mitochondrial; Nuclear receptor-binding factor 1; HsNrbf-1; mitochondrial trans-2-enoyl-CoA reductase], [MECR; MECR; NRBF1; CGI-63; FASN2B; NBRF1; HsNrbf-1; NRBF-1]
Gene, Accession #[MECR], Gene ID: 51102, NCBI: NP_057095, UniProt: Q9BV79
Catalog #MBS153654
Price$375
Order / More InfoMECR Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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