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Antigenic Specificity | MECR |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mg |
Concentration | 1 mg/mL |
Applications | ELISA (EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: At least two isoforms of MECR are known to exist; this antibody will detect both isoforms. MECR Antibody: The mitochondrial trans-2-enoyl-CoA reductase (MECR), was initially identified as nuclear receptor-binding factor 1 (NRBF1), which can interact with a multitude of nuclear hormone receptors in the presence of the respective ligands. MECR has been shown to be part of the mitochondrial fatty acid synthesis (FAS II) system and to catalyze the NAPDH-dependent reduction of 2-enoyl thioesters, generating saturated acyl-groups. Overexpression of this gene in transgenic mice can lead to cardiac abnormalities, suggesting that inappropriate expression of genes of FAS II can result in the development of hereditary cardiomyopathy. |
Immunogen | Immunogen: Rabbit polyclonal MECR antibody was raised against a 15 amino acid peptide near the carboxy terminus of human MECR. Buffer: MECR Antibody is supplied in PBS containing 0.02% sodium azide. |
Other Names | [MECR; NRBF1; CGI-63; FASN2B; NBRF1; Trans-2-enoyl-CoA reductase; mitochondrial; Nuclear receptor-binding factor 1; HsNrbf-1; mitochondrial trans-2-enoyl-CoA reductase], [MECR; MECR; NRBF1; CGI-63; FASN2B; NBRF1; HsNrbf-1; NRBF-1] |
Gene, Accession # | [MECR], Gene ID: 51102, NCBI: NP_057095, UniProt: Q9BV79 |
Catalog # | MBS153654 |
Price | $375 |
Order / More Info | MECR Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |